Advancing the Cloud Together: How AMD and AWS Are Powering the Next Era of Enterprise Efficiency and Innovation

In today’s cloud-first economy, enterprises are under growing pressure to achieve more with every workload. Cloud infrastructure is no longer just about scalability; it’s about aligning technology with business outcomes. That’s why AMD and AWS have forged a powerful collaboration that gives customers the freedom to innovate faster, run smarter, and operate more sustainably across the cloud.

At the center of this collaboration is a shared commitment to performance and choice. Together, AMD and AWS are helping organizations optimize cost, scale AI workloads efficiently, and accelerate innovation across industries—from digital services and financial institutions to manufacturers and public sector agencies. With AMD EPYC™ processor–powered Amazon EC2 instances, customers gain the flexibility and value to tailor their compute infrastructure to their business needs, whether they’re modernizing legacy systems, scaling cloud-native applications, or building AI-driven services.

Built for Business Outcomes

Across enterprises, CIOs and CTOs are aligning cloud strategy with measurable results: reducing total cost of ownership, improving energy efficiency, and supporting the rapid scaling of AI. Many enterprises now begin AI initiatives with a comprehensive cost assessment—prioritizing infrastructure that balances performance, power efficiency, and scalability. AMD EPYC processors, available across a broad range of Amazon EC2 instance families, are designed precisely for this balance.

When enterprises choose AMD EPYC CPU-powered instances on AWS, they can achieve outstanding performance per dollar, highly predictable scaling, and energy efficiency—all critical factors for modern cloud and AI workloads. Together, AMD and AWS are helping organizations move from experimentation to execution with cloud infrastructure that delivers tangible business impact.

Mission Cloud x AMD: Maximizing the Value of AWS Investments

A recent example of this collaboration in action is the new Mission Cloud x AMD strategic partnership, designed to help customers extract maximum value from their AWS investments. Mission Cloud works with enterprises to optimize performance and efficiency across AMD EPYC CPU-powered Amazon EC2 instances—helping customers balance cost, performance, and energy consumption without compromise.

Through this collaboration, enterprises gain a clear path to maximize the performance and value of their AWS environments. Together, Mission Cloud, CDW, and AMD are enabling organizations to modernize faster, unlock greater operational agility, and realize the full potential of their AWS investments.

The Next Generation of Amazon EC2 Instances

The collaboration between AMD and AWS continues to expand with the latest generation of AWS instances, powered by 5th Gen AMD EPYC processors. These new instances set a new bar for performance, scalability, and efficiency in the cloud. Amazon EC2 M8 Instances are available now. These instances deliver up to 30% more performance compared to the previous generation, making them ideal for web and application hosting, microservices architectures, and databases where consistent performance and efficient scaling are essential.

These innovations reflect a shared commitment by AMD and AWS to help customers do more with their cloud environments by pushing the limits of what’s possible in price-performance, efficiency, and scale.

Enabling the AI-Ready Enterprise

As AI continues to transform how businesses operate, infrastructure readiness is now a defining competitive advantage. AMD and AWS together are empowering enterprises to move from AI experimentation to enterprise-scale deployment.

The broad portfolio of AMD compute solutions, from CPUs to GPUs and adaptive accelerators, is integrated into AWS’s flexible and secure cloud platform. This combination gives customers the tools to deploy generative AI, predictive analytics, and high-performance computing (HPC) workloads with agility and confidence.

For many organizations, this partnership is the bridge between AI ambition and AI execution and helps IT leaders deploy infrastructure that’s optimized for both innovation and cost efficiency. Whether running AI model training in the cloud or scaling inference at the edge, enterprises can depend on the joint innovation between AMD and AWS to deliver the right performance for every stage of their AI journey.

An Open, Customer-First Ecosystem

At its core, the AMD + AWS relationship reflects a shared philosophy: openness, flexibility, and customer choice. Enterprises aren’t looking for one-size-fits-all infrastructure; they’re seeking trusted partners who enable seamless integration across multi-cloud and hybrid environments.

The AMD open ecosystem approach aligns perfectly with AWS’s mission to give customers freedom and control. Together, we’re helping businesses simplify operations, protect their data, and accelerate digital transformation without compromise.

Looking Ahead

The next chapter of cloud innovation will be defined by openness, performance efficiency, and AI readiness. Through its collaboration with AWS, AMD is committed to helping enterprises modernize their IT foundations, improve workload economics, and scale sustainably in the age of AI.

Learn more about AMD and AWS solutions here: https://aws.amazon.com/ec2/amd/ 

Join us at AWS re:Invent

We invite you to join us at AWS re:Invent to learn more about how AMD and AWS are shaping the future of enterprise cloud computing. Hear directly from industry experts, see demonstrations of AMD EPYC-powered Amazon EC2 instances in action, and explore how our joint innovations can help you advance your organization’s cloud strategy.