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The Right Server Tower for Your Customers

Reliable, Efficient, Built To Grow

Sell with confidence to SMB customers who need to run applications efficiently with the quiet, reliable Lenovo ThinkSystem ST45 V3, advanced by AMD EPYC 4000 Series server CPUs—an affordable solution that enables future growth opportunities.

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Why Sell the Lenovo ThinkSystem ST45 V3

Available Today

Compact, quiet and energy-efficient tower enables server deployment in offices, retail and branches—no data center required.

Server-grade reliability meets your customer's business demands.

Right-sized for your customer needs with scalable capacity—without unnecessary features.

Help Grow Revenue

Low-entry price with enterprise-class capability, enables you to offer high-value services that remain affordable as customers grow.

Supports evolving business demands, giving SMBs confidence their IT won’t hold them back.

AMD “Zen” cores are trusted in leading data centers, offering budget-friendly performance and efficiency for growing businesses.

Sell with Confidence

Lenovo and AMD bring enterprise-class technology, support and proven compatibility to help reduce risk for you and your customers.

AMD Infinity Guard helps protect data with features such as AMD Secure Boot, Transparent Secure Memory Encryption and Shadow Stack.1

ST45

The Lenovo ThinkSystem ST45 V3

Enterprise-level performance for SMBs

The Lenovo ThinkSystem ST45 V3 is the first Lenovo tower server to feature an AMD EPYC server CPU. With this product in your selling portfolio, you'll have an AMD based entry-level server with enterprise performance for SMBs.

Learn how compact server solutions like the Lenovo ST45 can support infrastructure modernization for your SMB customers.

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Upgrade to Windows Server 2025 with a Platform Designed to Maximize Value and Avoid Unnecessary Costs

AMD EPYC™ 4005 Series server CPUs offer up to 16 cores per socket, aligning cleanly with Windows Server core‑based licensing. This and other features help SMBs maximize their SW investment.

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Leadership Performance for Small Business Workloads

AMD EPYC 4000 Series server CPUs extend the leadership performance and efficiency of the 4th Gen AMD EPYC server CPU family into an expanded range of entry-level system use cases desired by small businesses. AMD EPYC 4000 Series server CPUs provide price and performance advantages over Intel.

Enterprise-class server at a budget price
Integer Performance
4C EPYC 4124P
1.34x
4C Xeon 6315P

AMD EPYC™ 4124P delivers 34% more performance at a 30% lower price compared to the Intel Xeon 6315P.2

Higher real-world performance
Integer Performance
16C EPYC 4545P
1.62x
8C Xeon 6369P

AMD EPYC™ 4545P is ~1.62x the overall performance of the Intel Xeon 6369P.3

Higher Windows Server 2025 OLTP throughput
New Orders Per Minute (NOPM)
EPYC 4545P
3.1x
Xeon 6357P
2.2X
Xeon E-2488

​AMD EPYC™ 4545P has ~3.1x the throughput of the Intel Xeon E-2488 (running Windows SQL Server 2025 OLTP workloads) .4

Sell with Confidence

Discover how the Lenovo ThinkSystem ST45 V3 stacks up against the Intel Xeon-powered Lenovo ThinkSystem ST50 V3 for performance, scalability and enterprise-ready reliability.

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Resources

AMD Partner Resources

Get up-to-date on everything you need to know about the newest features, capabilities and performance of AMD EPYC 4000 Series processors. These resources can enable you to better support SMB customers and help them confidently run their core business applications.

Explore Resources for Partners

AMD EPYC™ 4005 Series Server CPU for Windows Server 2025

A trusted, cost-effective Windows Server 2025 migration platform that helps you reduce customer risk and deliver measurable value.

Read the Benchmark Whitepaper
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AMD & Lenovo - A Trusted Collaboration

AMD and Lenovo work together to solve some of world’s greatest IT challenges. That experience provides you and your customers a trusted partner to help meet the challenges faced by SMB business today.

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Authorized Distributors

For current pricing and product availability, please contact your local distributor of choice.

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Contact Request

Lenovo Sales

Request contact from a Lenovo sales expert

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AMD Sales

Request contact from an AMD EPYC sales expert

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Footnotes
  1. GD-183A: AMD Infinity Guard features vary by EPYC™ Processor generations and/or series. Infinity Guard security features must be enabled by server OEMs and/or Cloud Service Providers to operate. Check with your OEM or provider to confirm support of these features. Learn more about Infinity Guard at https://www.amd.com/en/products/processors/server/epyc/infinity-guard.html.
  2. E4K-037: SPECrate®2017_int_base comparison based on published results as of 10/28/2025. Results and configurations below are in the format of: [processor], [cores], [TDP], [1Ku price in USD], [SPECrate®2017)_int_base score], [SPECrate® 2017)_int_base score / CPU W], [SPECrate® 2017)_int_base score / 1Ku price in USD], [Link to score] 1P AMD EPYC 4124P, 4C, 65W, $149 USD, 58.9, 0.906, 0.395, https://www.spec.org/cpu2017/results/res2025q1/cpu2017-20241216-45800.html 1P Intel Xeon 6315P, 4C, 55W, $213 USD, 43.8, 0.796, 0.206, https://www.spec.org/cpu2017/results/res2025q2/cpu2017-20250602-48610.html 1P Intel Xeon 6325P, 4C, 55W, $281 USD, 57.7, 1.049, 0.205, https://www.spec.org/cpu2017/results/res2025q2/cpu2017-20250518-48114.html Pricing as of 10/28/2025. Intel pricing from ark.intel.com. SPEC® and SPECrate® are registered trademarks of Standard Performance Evaluation Corporation. Learn more at spec.org.
  3. E4K-021B: Geometric Mean of 416 results based on Phoronix Test Suite paid testing as of 03/23/2026. 1P 6C AMD EPYC 4245P-powered server (65W TDP, $239 CPU $, 2 x 32GB DRAM-5600MT/s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB SAMSUNG MZ1L2960HCJR-00A07) 1P 8C AMD EPYC 4345P-powered server (65W TDP, $329 CPU $, 2 x 32GB DRAM-5600MT/s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB SAMSUNG MZ1L2960HCJR-00A07) 1P 16C AMD EPYC 4545P-powered server (65W TDP, $549 CPU $, 2 x 32GB DRAM-5600MT/s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB SAMSUNG MZ1L2960HCJR-00A07) 1P 16C AMD EPYC 4565P-powered server (170W TDP, $589 CPU $, 2 x 32GB DRAM-5600MT/s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB SAMSUNG MZ1L2960HCJR-00A07) 1P 16C AMD EPYC 4585PX-powered server (170W TDP, $699 CPU $, 2 x 32GB DRAM-5600MT /s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB SAMSUNG MZ1L2960HCJR-00A07) 1P 8C AMD EPYC 4364P-powered server (105W TDP, $399 CPU $, 2 x 32GB DRAM-5200MT/s, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB Micron_7450_MTFDKBA960TFR) 1P 12C AMD EPYC 4464P-powered server (65W TDP, $429 CPU $, 2 x 32GB DRAM-5200MT/s, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB Micron_7450_MTFDKBA960TFR) 1P 16C AMD EPYC 4564P-powered server (170W TDP, $699 CPU $, 2 x 32GB DRAM-5200MT/s, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB Micron_7450_MTFDKBA960TFR) 1P 8C Intel Xeon E-2488-powered server (95W TDP, $606 CPU $, 2 x 32GB DRAM-4800MT/s Micron MTC20C2085S1EC48BA1, 3201GB Micron_7450_MTFDKCC3T2TFS + 960GB Micron_7450_MTFDKBA960TFR) 1P 8C Intel Xeon 6369P-powered server (95W TDP, $606 CPU $, 2 x 32GB DRAM-4800MT/s Kingston, 3201GB Micron_7450_MTFDKCC3T2TFS) Model Geomean Rel2488 Rel6369P E-2488 224.948 1.000 0.965 6369P 233.101 1.036 1.000 4364P 261.396 1.162 1.122 4464P 301.719 1.341 1.294 4564P 361.903 1.609 1.553 4245P 269.797 1.199 1.157 4345P 320.473 1.425 1.375 4545P 377.935 1.68 1.621 4565P 426.123 1.894 1.828 4585PX 458.872 2.04 1.969 AMD 1Ku pricing and Intel ARK.intel.com specifications and pricing as of 03/23/2026. Testing not independently verified by AMD.
  4. E4K-035, E4K036, E4K037: Data provided by Principled Technologies,June 2026, source: https://www.principledtechnologies.com/AMD/EPYC-4545P-SMB-competitive-0626.pdf . Results not independently verified by AMD. MSSQL TPROC-C Workload is derived from TPC-Benchmark™ Standard, and as such is not comparable to published TPC-C™ results. TPC Benchmark, and TPC-C are trademarks of the TransactionProcessing Performance Council.

GD-83: Use of third party marks / logos/ products is for informational purposes only and no endorsement of or by AMD is intended or implied.

GD-97: Links to third party sites are provided for convenience and unless explicitly stated, AMD is not responsible for the contents of such linked sites and no endorsement is implied.