AMD Powers 4 of 10 Most Powerful Supercomputers, Advancing Global HPC and AI Leadership

AMD EPYC™ CPUs and AMD Instinct™ GPUs power leading systems across the latest TOP500 and Green500 rankings, delivering the performance and efficiency required for advanced scientific computing and AI. 

News Highlights: 

• AMD shows strong representation across the latest Top500 and Green500 rankings, powering 191 total systems, up 11% year-over-year, and 41% of the new systems in this year’s list.
• The Top500 and Green500 list highlights the performance and efficiency of AMD EPYC™ CPUs and AMD Instinct™ GPUs.
• Supercomputers across Europe showcase how AMD is helping advance the region’s sovereign AI and exascale computing ambitions.

The New TOP500 and Green500 lists demonstrate the scale of AMD leadership across global supercomputing, with our technology powering four of the world's 10 fastest and four of the 10 most-efficient supercomputers, and a total of 191 systems – an 11% increase year-over-year. 

Systems powered by AMD maintain a commanding presence in the 10 leading TOP500 systems, including El Capitan (No. 2) and Frontier (No. 3), along with the newly deployed HPC7 (No. 6). AMD EPYC CPUs and AMD Instinct GPUs serve as foundational technologies for many of the world’s most advanced systems, helping researchers and organizations accelerate scientific discovery and AI innovation.

Recognizing the most energy-efficient supercomputers in the world, the Green500 rankings are increasingly central to evaluating high-performance computing (HPC) capabilities. Our systems continue to rank among the most efficient in the world, with four systems placing in the Green500 top 10, including Otus (No. 5), Capella (No.6), AMD Ouranos (No. 9) and Portage (No. 10), while powering 56% of the top 50 systems. 

Together, these systems demonstrate how our architecture delivers the computational performance and energy efficiency required for the next era of AI and scientific discovery.

AMD Advances Europe’s Sovereign AI Ambitions 

While many AI conversations are centered on model size and training, our work with European computing leaders is taking a broader path — one rooted in scientific excellence, technological sovereignty and open collaboration. 

Across the region, AMD EPYC processors and AMD Instinct GPUs are powering new deployments across TOP500 supercomputing and AI projects. They include:

• Eni’s new HPC7 supercomputer (No. 6 in the TOP500) is one of Europe’s leading industrial HPC systems. Building on the success of HPC6 (No. 8 in the TOP500), Eni continues to support advanced AI, modeling and simulation workloads that help accelerate energy research while strengthening Europe’s sovereign AI and HPC capabilities.
• The first systems powered by AMD Instinct MI355X GPUs – two newly announced systems at the University of Cambridge – are ranked at Nos. 67 and 68 on the Top500 list. 
• LUMI, one of the world's fastest and most efficient supercomputers, has become a cornerstone of European AI research. Operated by the EuroHPC Joint Undertaking and hosted by CSC in Finland, LUMI (No. 11 in the TOP500) provides access to cutting-edge computational resources for both traditional HPC and advanced AI workloads. 
• GENCI, France’s national high-performance computing agency, is advancing its HPC and AI capabilities with AMD technology to support scientific research, advanced simulation and AI workloads. This includes the development of Alice Recoque, France’s first exascale supercomputer that will be powered by AMD Instinct MI430X GPUs and 6th Gen AMD EPYC CPUs. This system will support the need for HPC and AI, serving as an AI Factory.

Precision Still Matters

Many of the world’s most important scientific applications continue to rely on double-precision (FP64) computing. Whether modeling climate systems, simulating advanced materials, designing next-generation aircraft or exploring nuclear fusion, accuracy remains essential for producing trustworthy results.

At HPC User Forum 2026, we previewed the AMD Instinct MI430X GPU, designed specifically to address the growing need for both AI acceleration and leadership-class HPC performance.

AMD projects the AMD Instinct MI430X GPU will deliver more than 200 teraflops (TFLOPs) of native FP64 performance, which would establish a new benchmark for simulation, modeling and AI-driven scientific computing. This level of performance is critical as AI and HPC workloads increasingly converge on the same infrastructure. You can learn more at about our AMD Instinct MI430X GPUs at ISC High Performance 2026 (June 22-26) in Hamburg, Germany.