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AMD Instinct™ MI350X GPUs

Built on the 4th Gen AMD CDNA™ architecture, AMD Instinct™ MI350X GPUs deliver leadership AI and HPC performance for data center infrastructures with 288GB HBM3E memory, 8TB/s bandwidth, and expanded FP6 and FP4 datatype support.

View MI350X Brochure

View MI350X Platform Brochure

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Specs Comparisons

AI Performance
HPC Performance
Memory

AI Performance (Peak PFLOPs)

Up to 2X the AI performance vs. competitive accelerators¹

FP16/BF16 (Tensor/Matrix)

4.5

4.6

B200 SXM5 180GB

MI350X OAM 288GB

FP8 (PFLOPS) / INT8 (POPS)

9.2

B200 SXM5 180GB

MI350X OAM 288GB

FP6 (Sparsity)

18.5

B200 SXM5 180GB

MI350X OAM 288GB

HPC Performance (Peak TFLOPs)

Up to 1.9X the HPC performance vs. competitive accelerators²

FP64 (Vector)

B200 SXM5 180GB

MI350X OAM 288GB

FP64 (Tensor / Matrix)

B200 SXM5 180GB

MI350X OAM 288GB

FP32 (Vector)

144

B200 SXM5 180GB

MI350X OAM 288GB

Memory Capacity & Bandwidth

1.6X Memory Capacity vs. competitive accelerators³

Memory Capacity (GB)

180

288

B200 SXM5 180GB

MI350X OAM 288GB

Memory Bandwidth (TB/s)

7.7

8.0

B200 SXM5 180GB

MI350X OAM 288GB

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Support & Resources

AMD ROCm™ Software

Optimize GPU-accelerated applications with AMD ROCm™ software. Built on a code-once, use-everywhere approach.

ROCm Developer Hub About ROCm

AMD CDNA™ Architecture

Learn more about the architecture that underlies AMD Instinct GPUs.

Discover CDNA

AMD Instinct Documentation

Find documentation about AMD Instinct GPUs on the Documentation Hub.

See Docs

_{Certain AMD technologies may require third-party enablement or activation. Supported features may vary by operating system. Please confirm with system manufacturer for specific features. No technology or product can be completely secure.}

Footnotes

*TF32 support through software emulation.

Based on calculations by AMD Performance Labs in May 2025, to determine the peak theoretical precision performance for the AMD Instinct™ MI350X / MI355X GPUs, when comparing FP64, FP32, TF32, FP16, FP8, FP6 and FP4, INT8, and bfloat16 datatypes with Vector, Matrix, Sparsity or Tensor with Sparsity as applicable, vs. NVIDIA Blackwell B200 accelerator. Server manufacturers may vary configurations, yielding different results. MI350-009
Based on calculations by AMD Performance Labs in May 2025, to determine the peak theoretical precision performance for the AMD Instinct™ MI350X / MI355X GPUs, when comparing FP64 and FP32 with Vector, Matrix or Tensor as applicable, vs. NVIDIA Blackwell B200 accelerator. Results may vary based on server configuration, datatype, and workload. Performance may vary based on use of latest drivers and optimizations. MI350-019
Calculations conducted by AMD Performance Labs as of May 22nd, 2025, based on current specifications and /or estimation. The AMD Instinct™ MI355X OAM accelerators have 288GB HBM3e memory capacity and 8 TB/s GPU peak theoretical memory bandwidth performance. The highest published results on the NVidia Hopper H200 (141GB) SXM GPU accelerator resulted in 141GB HBM3e memory capacity and 4.8 TB/s GPU memory bandwidth performance. https://nvdam.widen.net/s/nb5zzzsjdf/hpc-datasheet-sc23-h200-datasheet-3002446 The highest published results on the NVidia Blackwell HGX B200 (180GB) GPU accelerator resulted in 180GB HBM3e memory capacity and 7.7 TB/s GPU memory bandwidth performance. https://nvdam.widen.net/s/wwnsxrhm2w/blackwell-datasheet-3384703 The highest published results on the NVidia Grace Blackwell GB200 (186GB) GPU accelerator resulted in 186GB HBM3e memory capacity and 8 TB/s GPU memory bandwidth performance. https://nvdam.widen.net/s/wwnsxrhm2w/blackwell-datasheet-3384703 MI350-001

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AMD Instinct™ MI350X GPUs

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